BISAP Score

Early mortality risk in acute pancreatitis — within the first 24 h

BUN > 25 mg/dL (urea > 8.9 mmol/L)

Impaired mental status

SIRS (≥ 2 criteria)

Age > 60 years

Pleural effusion on imaging

Evidence

Original publication

Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA. The early prediction of mortality in acute pancreatitis: a large population-based study. Derived and validated BISAP (BUN > 25 mg/dL, impaired mental status, SIRS, age > 60, pleural effusion); in-hospital mortality rose from < 1% at 0–1 points to > 20% at 5.

Gut, 2008

Open source

Guideline

The 2013 ACG acute pancreatitis guideline lists BISAP among the validated early scoring systems for identifying patients at risk of severe disease, to be combined with clinical judgement and response to resuscitation.

Last reviewed: 2026-09

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