Charlson Comorbidity Index

Weighted comorbidity burden and its approximate 1-year mortality
Myocardial infarction
Congestive heart failure
Peripheral vascular disease
Cerebrovascular disease (stroke or TIA)
Dementia
Chronic pulmonary disease
Connective tissue / rheumatic disease
Peptic ulcer disease
Hemiplegia or paraplegia
Moderate or severe renal disease
Diabetes mellitus
Liver disease
Malignancy
AIDS
Age
Evidence
Original publication
Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. Derived the weighted 17-category comorbidity index and the approximate 1-year mortality by score band used here (0: ~12%, 1–2: ~26%, 3–4: ~52%, ≥ 5: ~85%) from a cohort of 559 medical inpatients, validated in a second cohort of 685 patients.
Journal of Chronic Diseases, 1987
Open source
Guideline
The age-adjusted variant shown alongside the score (+1 point per decade of life from age 50, up to +5 at ≥ 90) is the form most commonly used in later research and clinical risk models; only the unadjusted score is mapped to the mortality figures above, which come from the 1987 derivation cohort — later populations and treatments have generally had better outcomes at a given score, and ICD-coded (Deyo/Quan) versions of the index can classify a small number of conditions differently from the original chart-review definitions.
Last reviewed: 2026-09
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