TIMI Risk Score (UA/NSTEMI)

Unstable angina / NSTEMI — 14-day event risk
Age 65 or older
3 or more CAD risk factors
Known coronary stenosis ≥ 50%
Aspirin use in the past 7 days
Severe angina (≥ 2 episodes in 24 h)
ST deviation ≥ 0.5 mm
Positive cardiac marker
Evidence
Original publication
Antman EM, Cohen M, Bernink PJLM, et al. The TIMI risk score for unstable angina/non-ST elevation MI: a method for prognostication and therapeutic decision making. Derived in TIMI 11B and validated in three additional cohorts (ESSENCE, TIMI 11B, PRISM-PLUS).
JAMA, 2000
Open source
Validation
Pollack CV Jr, Sites FD, Shofer FS, Sease KL, Hollander JE. Application of the TIMI risk score for unstable angina and non-ST elevation acute coronary syndrome to an unselected emergency department chest pain population.
Academic Emergency Medicine, 2006
Open source
Last reviewed: 2026-09
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