DAS28

Prevoo ML, van ’t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Derived DAS28 from tender and swollen 28-joint counts, an acute-phase reactant, and patient global health; it tracked the original DAS and discriminated treatment response.

EULAR recommends a treat-to-target strategy using a composite measure such as DAS28: < 2.6 remission, ≤ 3.2 low, > 3.2–≤ 5.1 moderate, > 5.1 high disease activity. DAS28-CRP tends to read slightly lower than DAS28-ESR near the remission cut-off.