Estimated creatinine clearance for renal drug dosing
Sex
Male
Female
Age (years)
Body weight (kg)
Serum creatinine
Enter age, weight, and serum creatinine to calculate
Evidence
Original publication
Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Derived from 249 hospitalised men; the female estimate applies a 0.85 multiplier. Uses actual body weight and non-standardised (Jaffe) creatinine.
Nephron, 1976
Open source
Guideline
Still widely referenced for renal drug dosing (many drug labels were studied against Cockcroft-Gault). It estimates creatinine clearance, not GFR, and is not used for CKD staging — use CKD-EPI for that.
Last reviewed: 2026-09
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MedScore is an educational and clinical decision-support tool. It does not provide a diagnosis, a treatment, or a drug-dosing recommendation, and it does not replace clinical judgement or local guidelines. Confirm every result against the original source before acting on it. The treating clinician remains responsible for all decisions.